Abstract: In order to achieve effective target detection with a radar network interfered by a moving radiation source, an adaptive suppression method based on Delay-Doppler alignment is proposed in this paper. First of all, the signal model for large baseline radar network interfered by a moving radiation source is built. Secondly the adaptive suppression is introduced in detail. Finally, the effectiveness of the method is verified via the simulation of a typical example. The results shows that the proposed method can take advantage of the target sparsity in RD plane and realize effective interference suppression.