深度全卷积网络对MRI膀胱图像的分割

Segmentation of MRI Bladder Images by Deep Fully Convolutional Network

  • 摘要: 大多数膀胱癌患者的膀胱肿瘤组织和膀胱壁组织互相渗透,各自的大小、形状变化多样,位置不固定,且膀胱MRI(Magnetic Resonance Imaging)图像中存在复杂的噪声和伪影,这使得将肿瘤和膀胱壁两者精确分割出来为下一步治疗进行诊断和定量分析成为难题。文中提出一种以U-net作为基础网络框架的深度全卷积网络,用残差网络子模块代替普通的卷积层进行下采样,通过空洞卷积来提取特征图不同感受野的信息,从而对不同尺度的特征图进行并行分支下采样。针对数据集小的问题,提出对图像加入高斯噪声、调节亮度和各向异性扩散滤波三种方法来进行数据扩增。实验结果表明,文中提出的方法对肿瘤分割的DSC(Dice similarity coefficient)值达到了0.9058,对膀胱壁分割的DSC值达到了0.9038,能够达到很好的分割效果。

     

    Abstract: Bladder tumor tissue and bladder wall tissue of most patients with bladder cancer penetrate each other, with variable size, shape, and position. And there are more complicated noises and artifacts in the image of bladder MRI. These maked the precise segmentation of both the tumor and the bladder wall becomes a problem for diagnosis and quantitative analysis of the next treatment. In this paper, a deep convolutional network with U-net as the basic network framework has been proposed. The residual network as a sub-module replaced the ordinary convolutional layer for downsampling, and the dilated convolution has been used to extract the information of different receptive fields in the feature map by parallel branch downsampling. Aiming at the problem with poor data sets, three methods of adding Gaussian noise, adjusting brightness and anisotropic diffusion filtering have been proposed for data augmentation. The experimental results shown that the method proposed in this paper got a DSC value of 0.9058 for bladder tumor, and the DSC value of the bladder wall segmentation reached 0.9038, which can achieve a good segmentation effect.

     

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