Abstract: Aiming at reliable target detection in large-baseline radar network, which is interfered by a single point radiation source, a dual-node adaptive cancellation method was proposed. This paper first established the echo signal model of a large baseline radar system under such environment. Then, based on the characteristics, a method combining coherent cancellation and non-coherent accumulation was derived. The proposed method was simulated and analyzed for the typical target and working scene. The preliminary results show that this method can achieve effective accumulation of target energy and cancellation of radiation source simultaneously, which has great application prospects.