改进的多模式脑肿瘤图像混合分割算法

An Improved Multi-Modal Brain Tumor Segmentation Hybrid Algorithm

  • 摘要: 脑肿瘤是一种高危疾病,在治疗过程中,任何有关位置和大小的信息都至关重要。为了有效检测和诊断脑肿瘤,针对多模式MRI脑肿瘤图像:FLAIR、T2和T1C,本文提出一种改进的多模式脑肿瘤图像混合分割算法。首先对三种模式的MRI图像分别进行中值滤波和快速模糊C均值聚类,之后将图像灰度值按照线性比例FLAIR:T2:T1C=5:4:1融合得到预处理图像。之后使用快速模糊C均值算法和自动阈值对预处理图像进行聚类分割,得到脑肿瘤的欠分割图像,最后,使用混合水平集算法对欠分割图像进行分割得到脑肿瘤分割图像。分割的脑肿瘤图像与金标准对比,平均Dice达到0.90;与同类算法对比,经本文算法得到的Dice最佳,稳定性好,实时性高,能够满足医学临床需要。

     

    Abstract: Brain tumor is a high-risk disease. The information about location and size is critical during treatment. In order to effectively detect and diagnose brain tumors, this paper presents an improved multi-modal brain tumor segmentation hydroid algorithm for multi-modal MRI brain tumor images: FLAIR, T2 and T1C. First, the preprocessing image is obtained by median filtering and fast fuzzy C-means clustering of MRI images of the three modals. And. the preprocessed image is linearly fused in the proportion of FLAIR:T2:T1C=5:4:1. Then, the fast fuzzy C-means algorithm is used to segment the preprocessed images, to produce the under-divided image of brain tumors. Finally, the under-divided images of brain tumors are processed by the mixed level set algorithm to obtain the segmented images of brain tumors. Compared with the gold standard, the average Dice of the result reached 0.90. Compared with other similar algorithms, the Dice is the best. the real-time and stability of ours algorithm are better, which could meet the clinical demand.

     

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