Abstract: There is not only target echo but also noise, clutter, and radio frequency interference (RFI) within through the wall radar echoes. A novel target echo enhancement method with amplitude weighting strategy along two-dimensional time domain data is proposed and two realization algorithms are carried out. Based on cross-shape sliding window processing, the method utilizes both fast and slow time domain echo within the sliding window to calculate weighted coefficients, and adjusts amplitude of overlap data between fast and slow time domain in order to improve the signal to noise ratio (SNR) and the signal to clutter ratio (SCR). Theoretical analysis and simulation results indicate that the method can enhance target echo effectively with just once or twice weighting processing when the sum of between echo signal to clutter and noise ratio (SCNR) in fast time domain and that in slow time domain is above 0 dB. Experimental results indicate that the method can decrease residual coupling, enhance amplitude of target echo, and be helpful to target detection and signature extraction.