Abstract: Aiming at the problem that the performance of asynchronous DS-CDMA system may be significantly degraded if a hostility jamming exists in system, we propose a blind joint jamming cancellation and multi-user detection scheme based on dual-antenna receiving for DS-CDMA system with hostility jamming. Taking the effect of hostile jamming into consideration, the algorithm firstly forms an overdetermined or determined blind source separation (BSS) model by treating the hostile jamming as multiple signals after series to parallel transformation , and then realizes blind jamming cancellation and multi-user detection by using BSS algorithm based on non-Gaussianity measure. The proposed scheme can realize multi-user detection and hostile jamming cancellation simultaneously without the knowledge of spread sequences and channel state information. Simulation results demonstrate that this scheme is valid for multiple kinds of hostile jamming.