Abstract: Based on the shortage of the current interference temperature model that reduces the interferences taken to primary users, this paper strengthens those users’ subjectivities in power control. Besides the game among secondary users to reduce their interferences due to the others by the adjustments in transmission powers and rates, the primary users detect the inferences taken by secondary users and use an interference punishment factor we designed under the premise that the inferences do not exceed the threshold. The more interference that the secondary user affects primary users, the more seriously that the secondary user will be punished. In this way, the transmission powers of secondary users and interferences that primary users affected will be reduced. The simulation results show that the proposed game-theoretic interference method could reduce interference and improve utility of primary users by decreasing secondary transmission powers. At the same time, the interferences among secondary users could also be reduced, and the received signal to interference will achieve some improvements.