Abstract: In order to better solve the existing problems of dynamic optimal interference management schemes for visible light communication (VLC) networks, an interference management scheme with both optimal power allocation and time slot allocation is proposed. At each time slot, firstly, access point (AP) coordinated sets for each user are established by the users’ location to eliminate interference, and all maximal independent sets including the largest number of non-interfered users are found. According to the difference of channel gain, for each maximal independent set the power is allocated to the channels by improved linear water-filling power allocation algorithm, which optimizes sum rate of each maximal independent set. Furthermore, considering the normalized priority factors involving sum rate, rate fairness and delay fairness, and the candidate maximal independent set with the maximum sum of priority factors is selected, in which the users involved are scheduled at the time slot. By simulation and comparison with the algorithms in representative literatures, the proposed interference management and resource allocation scheme have obvious advantages with spectrum utilization, energy efficiency, rate fairness and delay fairness.