Abstract: As macro and small cells coexistent in massive MIMO heterogeneous cellular networks (HetNets), an interference coordination strategy has been proposed to make up spatial blanking in terms of inter-group interference. To compensate the spatial blanking and eliminate interference between user groups, the strategy uses iteration to determine signal to interference plus noise ratio SINR, which is generated by user group within overlapping angular range on horizontal dimension and vertical dimension, and distinguishes different user groups, then serves each other. In order to reduce the complexity and inter-group interference caused by massive antenna, different pre-coding is adopted by macro-cell and small-cell. Simulation results show that this strategy can get higher user group rate and high-efficiency.